Research Cases for Use by the NIH Community
Theme 24 – Using AI in Research and Ethical Conduct of Clinical Trials (2024) (PDF file)
- Case Studies
- Case 1: IRB Protocol Deviation
- Case 2: Using AI to Write a Manuscript
- Case 3: Using AI to Analyze Research Data
- Case Study Facilitator Notes (PDF file)
- 2024 Ethics Case Facilitator Training with Dr. David Resnik (NIEHS) (external link)
- Note: IC submission of ethics case completion data is due by 02/28/2025
Theme 23 – Authorship, Collaborations, and Mentoring (2023) (PDF file)
- Case Studies
- Case 1: Transfer of a Project and Scientific Disagreement
- Case 2: Authorship or Acknowledgement of a Post-baccalaureate Trainee
- Case 3: Collaboration and Outside Activities
- Case Study Facilitator Notes (PDF file)
- 2023 Ethics Case Facilitator Training with Dr. David Resnik (NIEHS) (external link)
- 2023 Ethics Case Discussion Make-up Session (external link)
- Note: IC submission of ethics case completion data is due by 02/29/2024
Theme 22 – Use of Human Biospecimens and Informed Consent (2022) (PDF file)
- Case Study: Use of Human Biospecimens and Informed Consent
- Case Study Facilitator Notes (PDF file)
- 2022 Ethics Case Facilitator Training with Dr. David Resnik (NIEHS) (external link)
- Note: IC submission of ethics case completion data is due by 3/31/2023
Theme 21 – Science Under Pressure (2021) (PDF file)
- Case 1: Science Under Pressure
- Case 1 Facilitator Notes (PDF file)
- 2021 Ethics Case Facilitator Training with Dr. David Resnik (NIEHS) (external link)
Theme 20 – Data, Project and Lab Management, and Communication (2020) (PDF file)
- Case 1: Data Access, Analysis and Reporting within a Research Group
- Case 2: Postdoc Leaving NIH Lab
- Cases 1 and 2 for Facilitators (PDF file)
- 2020 Ethics Case Facilitator Training with Dr. David Resnik (NIEHS) (external link)
Theme 19 – Civility, Harassment and Inappropriate Conduct (2019) (PDF file)
- Case 1: Gender Harassment, Sexual Harassment, and Consenting Relationships
- Case 2: Freedom of Expression and Civility in the Laboratory
- Case 3: Biases in Mentoring of Fellows and Sexual Harassment
- Study Guide (2019) (PDF file)
Theme 18 – Implicit and Explicit Biases in the Research Setting (2018) (PDF file)
- Case 1: Gender Bias in Academia
- Case 2: Responsible and Equitable Mentoring of Fellows
- Case 3: Diversity and Bias – Approach to Disabilities
- Case 4: Implicit/Unconscious Biases?
Theme 17 – Socially Responsible Science (2017) (PDF file)
- Case 1: Deciding What Study Results to Publish and Transparency in Research Publication
- Case 2: Handling Select Agents
- Case 3: Research Competition and Reproducibility
- Case 4: Societal Aspects of the Responsible Conduct of Research
Theme 16 – Research Reproducibility (2016) (PDF file)
Because this important topic is both broad and provocative, with issues that could be discussed for hours, discussion leaders and participants will need to identify ways to keep the discussion on schedule. Three potential alternative approaches to this are: (a) keep discussion of the entire case concise and well-paced; (b) discuss a selected subset of the sections, labeled by Roman numerals, that are the most relevant to the particular IC and audience, and/or use only selected questions; or, (c) dedicate more than one hour to discussing this case.
- Case 1: Research Reproducibility
Theme 15 – Authorship and Collaborative Science (2015) (PDF file)
- Case 1: Intellectual Input, Core Facilities and Authorship
- Case 2: Authorship Disputes in Multi-Team Collaborations
- Case 3: Clinical Collaborations
- General Guidelines for Authorship Contributions (PDF file)
Theme 14 – Differentiating Between Honest Discourse and Research Misconduct and Introduction to Enhancing Reproducibility (2014) (PDF file)
- Case 1: Handling of Images and Graphs
- Case 2: A Technically Challenging Method Collides With a Hot Topic
- Case 3: Handling of Clinical Data
- Case 4: Sources of Potential Bias and Data Sharing
- Case 5: Research Reproducibility I: Sample Composition and Reproducibility
- Case 6: Research Reproducibility II: Prostate Cancer Serum Biomarker Study
Theme 13 – Data Management, Whistleblowers, and Nepotism (2013) (PDF file)
- Case 1: Whistleblowers
- Case 2: CLUES: Research Misconduct or Sloppy Science?
- Case 3: Data Management in Clinical Studies
- Case 4: Nepotism in the Training and Research Setting
Theme 12 – Mentoring (2012) (PDF file)
- Case 1: Different Mentoring Styles
- Case 2: Non-Academic Staff
- Case 3: Intellectual Property
- Case 4: Personal Relationships
Theme 11 – Authorship (2011) (PDF file)
- Case 1: Co-Authorship – When Changing Labs, Have You Done Enough to Be Included?
- Case 2: Criteria for Authorship and Attribution
- Case 3: Multiple Publications
- Case 4: First Authorship, Publicity, and Multiple Institutions
- General Guidelines for Authorship Contributions (PDF file)
- NIH IRP Authorship Conflict Resolution Process
Theme 10 – Science and Social Responsibility, Continued (2010) (PDF file)
- Case 1: Potential Consequences of Epidemiological Studies
- Case 2: Scientific Research and the Press
- Case 3: Intellectual Property – Why Use an MTA
Theme 9 – Science and Social Responsibility – Dual Use Research (2009) (PDF file)
- Case 1: Streptococcus pneumoniae Membrane Pump Sequence
- Case 2: Pandemic Influenza Genomic Sequence
- Case 3: An Unusual Wrinkle to Translational Research
- Case 4: Cell-matrix Interaction and Tumor Growth & Metastasis
Theme 8 – Borrowing – Is It Plagiarism? (2008) (PDF file)
- Case 1: Borrowing Results
- Case 2: Borrowing Ideas
- Case 3: Borrowing English
Theme 7 – Data Management and Scientific Misconduct (2007) (PDF file)
- Case 1: Data Management of Computer-generated Files
- Case 2: Handling of Images and Graphs
- Case 3: Appropriate Use of Statistics
- Case 4: Appropriate Sources of Data and Decision to Publish
- Case 5: Handling of Clinical Data
Theme 6 – Ethical Ambiguities (2006) (PDF file)
- Ethical Ambiguities
Theme 5 – Data Management (2005) (PDF file)
- Guiding Principles for Data Management (PDF file)
- Epidemiological and Clinical Data Management (PDF file)
- What’s in a Picture? The Temptation of Image Manipulation (PDF file)
- Three Retractions Published in Cell (2004) (PDF file)
Theme 4 – Collaborative Science (2004) (PDF file)
- Case 1: Basic-Clinical Collaboration
- Case 2: When Does a Collaborator Deserve Authorship
- Case 3: Equipment Sharing and Authorship
- Case 4: Assays and Authorship
- Case 5: Collaboration and Credit
- Case 6: The Statute of Limitations
Theme 3 – Mentoring (2003) (PDF file)
- Case 1: Different Supervising and Mentoring Styles
- Case 2: Equal Treatment of Postdoctoral Fellows Sharing of Job Ads
- Case 3: Work Hours and Schedules
- Case 4: Mentoring of Technicians
- Case 5: Intellectual Property Mentor’s Use of Fellow’s Research Proposal
- Case 6: Future Collaborations for Tenuretrack Investigators
- Case 7: Issues Related to CRADA Funding of Trainees
- Case 8: Confirmation of Lab Results Request for Secrecy
- Case 9: Handling of Personal Relationships in the Laboratory
- Case 10: Dealing with A Substance Abuse Problem in the Laboratory
- Useful Web Sites on Mentoring:
Theme 2 – Authorship (2002) (PDF file)
- Case 1: Authorship and the Role of the Absent Researcher
- Case 2: To Be or Not To Be Included
- Case 3: Student Publishes
- Case 4: Criteria for Authorship and Attribution
- Useful Web Sites on Authorship:
- http://www.stanford.edu/dept/DoR/rph/2-8.html (external link)
- http://www.responsibility.research.umich.edu/casematerialsdir.html (external link)
- http://www.apa.org/journals/amp/kurdek.html (external link)
- http://www.councilscienceeditors.org/services_ATF.shtml (external link)
- http://www.ed.gov/databases/ERIC_Digests/ed410318.html (external link)
Theme 1 – Scientific Misconduct (2001) (PDF file)
- Case 1: Scientific Misconduct in the Laboratory
- Case 2: Suspicions of Misconduct in Clinical Research
- Case 3: Ownership of Ideas (external link)
- Useful Links for Scientific/Research Misconduct:
This page was last updated on Thursday, August 8, 2024